Positron Emission Tomography for real-time verification during particle therapy di Peter Dendooven (PARTREC, University Medical Center Groningen)

Lunedi 23 gennaio 23 ore 15:00

Abstract:
In comparison to photon radiotherapy, particle beam radiotherapy (mostly protons and carbon ions are used) results in a lower radiation dose to normal tissue, reducing longterm complications and increasing the quality of life of patients. However, the dose distribution delivered during particle therapy is quite sensitive to anatomical changes in the patient, particle range uncertainties and patient setup errors. Because of this, several techniques for invivo dose delivery verification have and are being developed. The most investigated method is positron emission tomography (PET) of the positron emitters that are created by the particles via nuclear reactions in the patient. The PET signal is obviously delayed by the radioactive decay halflife. For most positron emitters this precludes realtime feedback and leaves room for biological washout. I will report on investigations towards realtime verification using PET during proton, helium ion and heavy ion therapy. At the University Medical Center Groningen, we are investigating imaging of 12 N, with a halflife of just 11 ms, produced by the proton or helium beam in the patient. I will report on recent proofofprinciple demonstrations of the range accuracy in homogeneous targets, and discuss our present research to
establish the clinical relevance on the basis of irradiations of an anthropomorphic head phantom. Treatment with positron emitting radioactive heavy ions gives a much stronger PET signal which is more closely correlated to the Bragg peak compared to treatment with stable heavy ions. Within the BARB project at the GSI Helmholtzzentrum für Schwerionenforschung, we have investigated the precision with which the range of 10,11 C and 14,15 O can be measured using PET. The design and outcome of these experiments will be discussed.

Il seminario si terrà in presenza nella sala Galilei (131) e via zoom al seguente indirizzo: https://infn-it.zoom.us/j/84261721878?pwd=MDZNaGdBUlcvUUJXa2phSHZVZk5sdz09

Lattice QCD computation of the muon magnetic moment (Prof. Szabo KALMAN, University of Wuppertal)

Abstract: The muon is an elementary particle, a short-lived cousin of the electron. Since about 20 years the calculation of its magnetic moment disagrees with its measurement, indicating that a not-yet-known particle or force might be influencing the muon. An experiment at the Fermi National Accelerator Laboratory (FNAL,US) confirmed this puzzling discrepancy with an announcement in April 2021. The event received significant media attention. 

At the same time our group published a new ab-inito calculation, based on lattice formulation of quantum chromodynamics (lattice QCD), which challenged previous computations and brought the theoretical prediction closer to the experimental value. According to this result, no new forces or particles are neccessary to explain the FNAL and previous measurements.

Currently, the question if there is any new physics in the muon magnetic moment, is open. Since 2021 several new independent lattice QCD computations have appeared, there are updates of the old style theory approach, and also comparisons of the two approaches. In the meantime the FNAL experiment keeps on gathering new data.

The talk will give a review of these efforts with the main focus on our original lattice computation.
Il seminario si terrà in presenza nella sala riunioni 250 e via zoom al seguente indirizzo:  https://infn-it.zoom.us/j/84261721878?pwd=MDZNaGdBUlcvUUJXa2phSHZVZk5sdz09

Cold ion-molecule interactions relevant for astrochemistry (Heather J. Lewandowski, JILA and Department of Physics, University of Colorado at Boulder, USA)

Abstract: Control over the quantum states of atoms and molecules can lead to a fundamentally new understanding of how these particles interact and react. This knowledge has the potential to impact our ability to probe processes in planetary atmospheres and in the interstellar medium. Experimental techniques developed for control and measurement of atoms is now being used to study more and more complex molecules. We study these rich systems at low temperatures where we can trap and examine their properties for many minutes, as compared to small fractions of a second in standard experiments. Using these cold, trapped molecular ions, we investigate mechanisms of ion-molecule reactions to gain insights into the mechanisms driving these processes. In particular, we explore possible mechanisms that may initiate growth of carbon chains in the interstellar medium.

Intelligence for digital REStoration of Cultural Heritage (AIRES-CH) di Alessandro Bombini (INFN – Firenze)

Abstract:

Artificial Intelligence for digital REStoration of Cultural Heritage (AIRES-CH) is a project focused on a creation of a cloud-native web app for the digital restoration of pictorial artworks through Computer Vision technologies applied to nuclear imaging raw data, such as X-Ray Fluorescence (XRF). In this talk, after a really brief introduction on nuclear imaging technologies, I will show that the task of associating an RGB colour image to an XRF imaging raw data is feasible by means of a multidimensional neural network, by discussing the Deep Neural Network models pipeline (training dataset composition, models’ architecture definition, training process, hyperparameter optimisation, validation); I will close with a brief discussion on how the trained neural network is employed in the cloud-native web application for XRF raw data real-time analysis.

 
Il seminario si terrà in presenza nella sala riunioni 250 e via zoom al seguente indirizzo: 

 

“Probing Flavor in semileptonic transitions at High-pT” (Florentin Jaffredo, INFN – Pisa)

Abstract: The Drell-Yan processes pp->ll and pp->l nu at high transverse momentum can provide important probes of semileptonic transitions that are complementary to low-energy flavor physics observables. We parametrize possible New Physics contributions to these processes in terms of form-factors, and derive the corresponding bounds by recasting the latest ATLAS and CMS run 2 searches for mono- and di-lepton resonances. Moreover, we study the validity limit of the Standard Model Effective Field Theory (SMEFT) in this regime by comparing the limits obtained for specific tree-level mediators and their EFT equivalent. Both analyses are performed using HighPT, a new Mathematica package for automatic extraction of high-pT bounds.
 
 
Il seminario si terrà in presenza nella sala riunioni 131 e via zoom al seguente indirizzo: https://infn-it.zoom.us/j/84261721878?pwd=MDZNaGdBUlcvUUJXa2phSHZVZk5sdz09
 

Everything you wanted to know about New Physics and Core-collapse Supernovae: but were afraid to ask (Andrea Caputo – CERN)

AbstractCore-collapse supernovae (CCSN) are efficient laboratories to explore physics beyond the standard model (SM). In particular, they have been used to put strong constraints on axion and axion like particles, and on many other motivated extensions of the SM. In this talk I will first introduce the subject and then focus on some new results for muon-philic interactions. Finally, I will also describe a particular class of CCSNe, the Low Energy CCSNe, and show how they can be used as efficient beam dump experiments to severely constrain radiative particle decays..
 
Il seminario si terrà in presenza nella sala riunioni 131 e via zoom al seguente indirizzo: 
 

We are thrilled to announce that the Conference “DarkCosmoGrav: New Frontiers in Particle Physics, Gravity, and Cosmology” will take place in January 23-24-25, 2023, at the University of Pisa

 


The aim of this event is twofold. On the one hand, by hosting world-renowned experts in these subjects, we want to critically review recent progresses in particle physics, gravity and cosmology, especially underlining their connections. On the other hand, the goal is to bring together researchers from different but tightly connected research areas to increase the exchange of ideas between them and give the participants the possibility to start new and exciting collaborations.

From the scientific standpoint, given the recent theoretical and experimental developments in high energy physics and cosmology, it is becoming crucial to better understand the connection between these fields. Indeed, cosmological observations are becoming increasingly more important for both the particle physics and gravity communities. In fact, our understanding of Nature accounts for only about 5% of the content of the Universe, whereas the remaining elusive ingredients strongly point at new physics beyond our standard paradigms, both at the smallest and at the largest scales. It is therefore essential to investigate the theoretical and phenomenological developments in all of these areas, while also increasing the communication between them.


DarkCosmoGrav will feature:

  • Six plenary speakers
  • 24 talks
  • Evening poster session
  • Round table
  • Special Talk

We warmly invite you to come and present your work with a talk or a poster and to join in stimulating discussions covering all aspects in the fields of particle physics, gravity and cosmology, with a special emphasis on the topics at their intersections. We particularly encourage the participation of young researchers.


In DarkCosmoGrav, respect and inclusiveness are key ingredients, thus all attendees must abide by the code of conduct.

All talks will be broadcast on Zoom. Further information will be communicated to the participants.

For information regarding travel and accommodation, please review the venue and accommodation tabs.

 

 

 

 

 

 


 

This conference is sponsored by:

                                                                                                                

 
 
 
 

Nepsi23 – New Physics Signal 2023 – February 15-17, 2023

Young Organization for Young Researchers 

 

New Physics Signals (NePSi – NeΨ) is the 1ˢᵗ International Workshop completely organized by Young Researchers which supports the active participation of Young Researchers.

The organization provides alternating Senior and Young Researchers sessions. This gives the opportunity to early stage researchers, severely penalized by the pandemic, to spread their work and, also, to experienced academic to be aware about the innovative ideas coming from the newcomers. 

NeΨ 2023 will take place in the Aula Magna “Fratelli Pontecorvo” at the Physics Department “E. Fermi” of the University of Pisa.

It aims at bringing together the theoretical and experimental communities, to create a discussion table to settle the main results recently obtained in the context of high-energy physics.

The event includes oral presentations on the most promising tests concerning the physics beyond the Standard Model, the tensions that have already been reduced in the sector of Flavor physics, and the ones that still require a deeper investigation. The ultimate goal is to draw a common path for the search of New Physics, especially in view of the improved precision that will be achieved by current and future collider experiments (e.g., Belle II and LHCb Upgrade II).

The registration as a listener is reserved for participants without contribution (talk/poster) in a maximum number of 60 people. Invited speakers can instead already register as presenters.

Young researchers are strongly invited to apply for a contribution too! Abstract of the talk/poster can be submitted for approval by the Organizing Committee via the dedicated form. In this case we recommend registration after the committee decision. 

Finally, we will also allow for remote attendance to the workshop for a limited number of participants.

 

Please check the indico page for further details https://agenda.infn.it/e/nepsi23